1. a painful and debilitating infestation contracted by drinking stagnant water contaminated with Guinea worm larvae that can mature inside a human's abdomen until the worm emerges through a painful blister in the person's skin • Syn: Guinea worm disease, dracunculiasis • Hypernyms: infestation 2. parasitic roundworm of India and Africa that lives in the abdomen or beneath the skin of humans and other vertebrates • Syn: Dracunculus medinensis • Hypernyms: nematode, nematode worm, roundworm • Member Holonyms: Dracunculus, genus Dracunculus